Flomoxef sodium

• CAT Number: I018756
• CAS Number: 92823-03-5
• Molecular Formula: C₁₅H₁₇F₂N₆NaO₇S₂
• Molecular Weight: 518.45
• Purity: ≥95%
• IUPAC Name: sodium;(6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• InChI: InChI=1S/C15H18F2N6O7S2.Na/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24;/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27);/q;+1/p-1/t12-,15+;/m1./s1
• InChIKey: PPPZBOLFWGINKN-YLCXCWDSSA-M
• SMILES: CO[C@@]1([C@@H]2N(C1=O)C(=C(CO2)CSC3=NN=NN3CCO)C(=O)[O-])NC(=O)CSC(F)F.[Na+]

Flomoxef sodium（Cat No.:I018756）is a broad-spectrum, semisynthetic cephalosporin antibiotic used primarily for treating infections caused by Gram-negative and Gram-positive bacteria. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Flomoxef sodium is effective against a variety of infections, including respiratory, urinary tract, and skin infections. Its unique structure provides enhanced stability against β-lactamase enzymes, making it useful in resistant infections. Typically administered intravenously, it is commonly used in hospital settings under careful medical supervision for managing severe infections.

Reference

[1]. Yazawa K, et al. In-vitro activity of flomoxef, a new oxacephem group antibiotic, against Nocardia in comparison with other cephalosporins. J Antimicrob Chemother. 1989 Dec;24(6):921-5.[2]. Simon C, et al. In vitro activity of flomoxef in comparison to other cephalosporins. Infection. 1988 Mar-Apr;16(2):131-4.