For research use only. Not for therapeutic Use.
Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases[1][2].
| Catalog Number | R003496 |
| CAS Number | 108656-33-3 |
| Synonyms | (1R,2S)-2-amino-3-fluoro-1-(4-methylsulfonylphenyl)propan-1-ol;hydrochloride |
| Molecular Formula | C10H15ClFNO3S |
| Purity | ≥95% |
| InChI | InChI=1S/C10H14FNO3S.ClH/c1-16(14,15)8-4-2-7(3-5-8)10(13)9(12)6-11;/h2-5,9-10,13H,6,12H2,1H3;1H/t9-,10-;/m1./s1 |
| InChIKey | HWPBPTAOXVIKGI-DHTOPLTISA-N |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)N)O.Cl |
| Reference | [1]. B-K Park, et al. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus). J Vet Pharmacol Ther. 2006 Feb;29(1):37-40. [2]. Anadón A, et al. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 2008 Nov 26;56(22):11049-56. |
