Flucloxacillin Sodium

• CAT Number: R007873
• CAS Number: 1847-24-1
• Molecular Formula: C19H16ClFN3NaO5S
• Molecular Weight: 475.85
• Purity: ≥95%
• Synonyms: (2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium; Floxacillin Sodium; Floxapen Sodium; Floxapen Sodium; Staphylex Sodium
• Target: Bacterial
• Storage: Store at -20°C
• IUPAC Name: sodium;(2S,5R,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChI: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]
• InChIKey: InChI=1S/C19H17ClFN3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/q;+1/p-1/t13-,14+,17-;/m1./s1

Flucloxacillin Sodium（Cat No.:R007873）is a beta-lactam antibiotic in the penicillin class, primarily used to treat infections caused by penicillinase-producing staphylococci and other Gram-positive bacteria. It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. This antibiotic is commonly prescribed for skin and soft tissue infections, respiratory infections, and bone infections such as osteomyelitis. Flucloxacillin Sodium is particularly valued for its resistance to bacterial beta-lactamase enzymes, making it effective where other penicillins might fail, and is widely used in both clinical and research settings to address bacterial resistance.

Reference

Guzmán, Flavio, MD. /Beta Lactams Antibiotics (penicillins and Cephalosporins) Mechanism of Action.” Medical Pharmacology. Pharmacology Corner, 29 Nov. 2008. Web. 21 Aug. 2012.Pitout JD, Sanders CC, Sanders WE Jr. Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli. Am J Med 1997; 103:51.