Flucytosine

• CAT Number: A000838
• CAS Number: 2022-85-7
• Molecular Formula: C4H4FN3O
• Molecular Weight: 129.10
• Purity: ≥95%
• Synonyms: 5-Fluorocytosine; Flucytosine; 2022-85-7; Ancotil; Ancobon; Flucytosin
• Target: Antibiotic
• Solubility: >6.4mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 6-amino-5-fluoro-1H-pyrimidin-2-one
• InChI: InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
• InChIKey: XRECTZIEBJDKEO-UHFFFAOYSA-N
• SMILES: C1=NC(=O)NC(=C1F)N

Flucytosine（Cat No.:A000838）is a fluorinated pyrimidine analog with potent antifungal activity, commonly used in research and clinical applications. It targets fungal cells by converting into 5-fluorouracil, disrupting RNA and DNA synthesis. Effective against Candida, Cryptococcus, and certain molds, Flucytosine is often combined with other antifungal agents, such as amphotericin B, to enhance efficacy and reduce resistance. Its unique mechanism and selective toxicity to fungal cells make it a valuable tool in antifungal drug development. Research focuses on optimizing dosing and managing resistance for improved therapeutic outcomes.

Reference

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