For research use only. Not for therapeutic Use.
Fluensulfone（Cat No.:I006811）is a novel nematicide used in agriculture to control plant-parasitic nematodes, including root-knot nematodes (Meloidogyne spp.). It disrupts nematode energy metabolism by inhibiting key enzymes involved in their biological processes, leading to paralysis and death. Unlike many traditional nematicides, fluensulfone offers a favorable environmental profile with reduced toxicity to non-target organisms and minimal residual impact on soil health. It is applied as a soil treatment, providing effective control and improving crop yield and quality. Fluensulfone is a vital tool in integrated pest management strategies.
| Catalog Number | I006811 |
| CAS Number | 318290-98-1 |
| Synonyms | Fluensulfone;5-chloro-2-(3,4,4-trifluorobut-3-ene-1-sulfonyl)-1,3-thiazole |
| Molecular Formula | C7H5ClF3NO2S2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | 5-chloro-2-(3,4,4-trifluorobut-3-enylsulfonyl)-1,3-thiazole |
| InChI | InChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13,14)2-1-4(9)6(10)11/h3H,1-2H2 |
| InChIKey | XSNMWAPKHUGZGQ-UHFFFAOYSA-N |
| SMILES | C1=C(SC(=N1)S(=O)(=O)CCC(=C(F)F)F)Cl |
| Reference | </br>1:Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors. II: Additional Mechanistic Studies. Strupp C, Bomann W, Cohen SM, Weber K.Toxicol Sci. 2016 Dec;154(2):296-308. Epub 2016 Sep 7. PMID: 27605420 </br>2:Efficacy of Various Application Methods of Fluensulfone for Managing Root-knot Nematodes in Vegetables. Morris KA, Langston DB, Davis RF, Noe JP, Dickson DW, Timper P.J Nematol. 2016 Jun;48(2):65-71. PMID: 27418698 Free PMC Article</br>3:Field evaluation of the nematicide fluensulfone for control of the potato cyst nematode Globodera pallida. Norshie PM, Grove IG, Back MA.Pest Manag Sci. 2016 Oct;72(10):2001-7. doi: 10.1002/ps.4329. Epub 2016 Jul 4. PMID: 27241192 Free PMC Article</br>4:Efficacy of Fluensulfone in a Tomato-Cucumber Double Cropping System. Morris KA, Langston DB, Dickson DW, Davis RF, Timper P, Noe JP.J Nematol. 2015 Dec;47(4):310-5. PMID: 26941459 Free PMC Article</br>5:Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones. Kearn J, Ludlow E, Dillon J, O/’Connor V, Holden-Dye L.Pestic Biochem Physiol. 2014 Feb;109:44-57. doi: 10.1016/j.pestbp.2014.01.004. Epub 2014 Jan 31. PMID: 24581383 Free Article</br>6:Nematicidal activity of fluensulfone against some migratory nematodes under laboratory conditions. Oka Y.Pest Manag Sci. 2014 Dec;70(12):1850-8. doi: 10.1002/ps.3730. Epub 2014 Feb 25. PMID: 24452922 </br>7:Influence of soil environments on nematicidal activity of fluensulfone against Meloidogyne javanica. Oka Y, Shuker S, Tkachi N.Pest Manag Sci. 2013 Nov;69(11):1225-34. doi: 10.1002/ps.3487. Epub 2013 Mar 1. PMID: 23456999 </br>8:Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework. Strupp C, Banas DA, Cohen SM, Gordon EB, Jaeger M, Weber K.Toxicol Sci. 2012 Jul;128(1):284-94. doi: 10.1093/toxsci/kfs127. Epub 2012 Apr 5. PMID: 22491425 Free PMC Article</br>9:Systemic nematicidal activity of fluensulfone against the root-knot nematode Meloidogyne incognita on pepper. Oka Y, Shuker S, Tkachi N.Pest Manag Sci. 2012 Feb;68(2):268-75. doi: 10.1002/ps.2256. Epub 2011 Aug 12. PMID: 21842527 |
