Flumazenil acid

For research use only. Not for therapeutic Use.

  • CAT Number: I009090
  • CAS Number: 84378-44-9
  • Molecular Formula: C13H10FN3O3
  • Molecular Weight: 275.24
  • Purity: ≥95%
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Flumazenil acid is a metabolite of Flumazenil[1]. Flumazenil is a GABAA receptor antagonist[2].


Catalog Number I009090
CAS Number 84378-44-9
Synonyms

8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid

Molecular Formula C13H10FN3O3
Purity ≥95%
InChI InChI=1S/C13H10FN3O3/c1-16-5-10-11(13(19)20)15-6-17(10)9-3-2-7(14)4-8(9)12(16)18/h2-4,6H,5H2,1H3,(H,19,20)
InChIKey SFVXVWJBSJCRJO-UHFFFAOYSA-N
SMILES CN1CC2=C(N=CN2C3=C(C1=O)C=C(C=C3)F)C(=O)O
Reference

[1]. Kleingeist B, et al. Isolation and pharmacological characterization of microsomal human liver flumazenil carboxylesterase. J Pharm Pharm Sci. 1998 Jan-Apr;1(1):38-46.
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[2]. Mograbi KM, et al. Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson’s disease model in mice. Physiol Rep. 2017 Mar;5(6). pii: e13081.
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