For research use only. Not for therapeutic Use.
Flumazenil acid is a metabolite of Flumazenil[1]. Flumazenil is a GABAA receptor antagonist[2].
Catalog Number | I009090 |
CAS Number | 84378-44-9 |
Synonyms | 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid |
Molecular Formula | C13H10FN3O3 |
Purity | ≥95% |
InChI | InChI=1S/C13H10FN3O3/c1-16-5-10-11(13(19)20)15-6-17(10)9-3-2-7(14)4-8(9)12(16)18/h2-4,6H,5H2,1H3,(H,19,20) |
InChIKey | SFVXVWJBSJCRJO-UHFFFAOYSA-N |
SMILES | CN1CC2=C(N=CN2C3=C(C1=O)C=C(C=C3)F)C(=O)O |
Reference | [1]. Kleingeist B, et al. Isolation and pharmacological characterization of microsomal human liver flumazenil carboxylesterase. J Pharm Pharm Sci. 1998 Jan-Apr;1(1):38-46. [2]. Mograbi KM, et al. Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson’s disease model in mice. Physiol Rep. 2017 Mar;5(6). pii: e13081. |