Flumequine

• CAT Number: A001186
• CAS Number: 42835-25-6
• Molecular Formula: C14H12FNO3
• Molecular Weight: 261.30
• Purity: ≥95%
• Target: Cell Cycle/DNA Damage
• Solubility: >9.4mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: 7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid
• InChI: InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
• InChIKey: DPSPPJIUMHPXMA-UHFFFAOYSA-N
• SMILES: CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O

Flumequine（Cat No.:A001186）is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine to treat bacterial infections in animals, especially in aquaculture and poultry. It works by inhibiting bacterial DNA gyrase, an enzyme essential for DNA replication and cell division, leading to bacterial death. Flumequine is effective against a range of Gram-negative bacteria, particularly in treating urinary tract and gastrointestinal infections. Due to its specificity and effectiveness, it helps control infections in agricultural settings, although its use is restricted in some regions to minimize the risk of antibiotic resistance development.

Reference

Wolfson, John S., and David C. Hooper. /The Fluoroquinolones: Structures, Mechanisms of Action and Resistance, and Spectra of Activity in Vitro./ American Society for Microbiology 4th ser. 28 (1985): 581-86.