Flumethasone-d3

• CAT Number: R050789
• CAS Number: NA
• Molecular Formula: C₂₂H₂₅D₃F₂O₅
• Molecular Weight: 413.47
• Purity: ≥95%
• Synonyms: (6α,11β,16α)-6,9-Difluoro-11,17,21-trihydroxy-16-(methyl-d3)pregna-1,4-diene-3,20-dione; 6α,9α-Difluoro-16α-(methyl-d3)prednisolone; 6α-Fluorodexamethasone-d3; 6α-Fluorodexamethazone-d3; Anaprime-d3; Aniprime-d3; Aniprome-d3; Cortexillar-d3; Flucort-
• Storage: -20°C
• IUPAC Name: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-(trideuteriomethyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1/i1D3
• InChIKey: WXURHACBFYSXBI-SLFSQGSYSA-N
• SMILES: [2H]C([2H])([2H])[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)F

Flumethasone-d3 is an isotopically labeled form of flumethasone, a potent corticosteroid used in anti-inflammatory and immunosuppressive therapies. This compound features three deuterium atoms, making it particularly useful in pharmacokinetic studies, where precise tracking of the drug’s metabolism and distribution is required. The deuterium labeling enhances the accuracy of mass spectrometric analyses, allowing researchers to differentiate between the labeled and non-labeled versions of flumethasone in biological samples. Flumethasone-d3 is crucial for drug development research, helping to elucidate the metabolic pathways and optimize the therapeutic efficacy of corticosteroids. Its high purity and stability make it a reliable tool in advanced pharmaceutical investigations.