Flunarizine dihydrochloride

• CAT Number: I013875
• CAS Number: 30484-77-6
• Molecular Formula: C₂₆H₂₈Cl₂F₂N₂
• Molecular Weight: 477.42
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: 10 mM in DMSO
• IUPAC Name: 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride
• InChI: InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+
• InChIKey: RXKMOPXNWTYEHI-RDRKJGRWSA-N
• SMILES: C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl

Flunarizine Dihydrochloride(CAT: I013875) is a selective calcium channel blocker widely used in neurological and cardiovascular research. It inhibits voltage-dependent calcium influx, particularly affecting L-type calcium channels, and exhibits antihistaminic, vasodilatory, and neuroprotective properties. Flunarizine Dihydrochloride is extensively studied for its potential therapeutic applications in conditions such as migraine prophylaxis, vertigo, and cerebrovascular disorders. Its ability to modulate calcium-dependent signaling pathways makes it a valuable tool for exploring the mechanisms of calcium channel regulation and its impact on neuronal excitability and vascular function. With high purity and stability, it is suitable for both in vitro and in vivo studies, advancing drug discovery in neurology and related fields.