Flunisolide

• CAT Number: I000040
• CAS Number: 3385-03-3
• Molecular Formula: C24H31FO6
• Molecular Weight: 434.50
• Purity: ≥95%
• Synonyms: (6α,11β,16α)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; 6α-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)?pregna-1,4-diene-3,20-dione; Aerobid; Aerobid M; Bronalide; Flunisolide; Lunis; Nasalide
• Target: Vitamin D Related/Nuclear Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
• InChI: InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
• InChIKey: XSFJVAJPIHIPKU-XWCQMRHXSA-N
• SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@]35C)F)O

Flunisolide (Cat.No:I000040) is a synthetic corticosteroid commonly used to treat asthma and allergic rhinitis by reducing inflammation in the airways. Administered via inhalation or nasal spray, it alleviates symptoms such as congestion, wheezing, and difficulty breathing. Flunisolide works by suppressing immune responses that trigger airway inflammation, providing effective and targeted relief. Its localized action minimizes systemic side effects, making it suitable for long-term management. Additionally, it is studied for its potential applications in chronic respiratory conditions like COPD and nasal polyps.