Fluocortolone 21-Hexanoate

• CAT Number: R047642
• CAS Number: 303-40-2
• Molecular Formula: C28H39FO5
• Molecular Weight: 474.613
• Purity: 95%
• Synonyms: (6α,11β,16α)-6-Fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]pregna-1,4-diene-3,20-dione; 6α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Hexanoate; Ficoid; Fluocortolone Caproate; Fluocortolone Hexanoate
• Appearance: Solid
• Storage: -20°C
• IUPAC Name: [2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hexanoate
• InChI: InChI=1S/C28H39FO5/c1-5-6-7-8-24(33)34-15-23(32)25-16(2)11-19-18-13-21(29)20-12-17(30)9-10-27(20,3)26(18)22(31)14-28(19,25)4/h9-10,12,16,18-19,21-22,25-26,31H,5-8,11,13-15H2,1-4H3/t16-,18+,19+,21+,22+,25-,26-,27+,28+/m1/s1
• InChIKey: WHZRCUIISKRTJL-YTZKRAOUSA-N
• SMILES: CCCCCC(=O)OCC(=O)C1C(CC2C1(CC(C3C2CC(C4=CC(=O)C=CC34C)F)O)C)C

Fluocortolone 21-hexanoate is a corticosteroid derivative used in pharmaceutical formulations for its anti-inflammatory and immunosuppressive properties. This compound is often employed in topical medications to alleviate inflammation and itching associated with various dermatological conditions, including eczema and psoriasis. Fluocortolone 21-hexanoate functions by inhibiting the release of inflammatory mediators and suppressing immune responses. Research on this compound aims to optimize its formulation for effective dermatological therapy while minimizing side effects and enhancing patient compliance.