For research use only. Not for therapeutic Use.
Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].
| Catalog Number | I011678 |
| CAS Number | 531-46-4 |
| Synonyms | 6,11-dihydroquinoxalino[2,3-b]quinoxaline |
| Molecular Formula | C14H10N4 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H10N4/c1-2-6-10-9(5-1)15-13-14(16-10)18-12-8-4-3-7-11(12)17-13/h1-8H,(H,15,17)(H,16,18) |
| InChIKey | WGKYYZDYHYOKQV-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)NC3=NC4=CC=CC=C4N=C3N2 |
| Reference | [1]. SJ Brown, et al. Probe Report for NOX1 Inhibitors. |
