Fluorescein-6-isothiocyanate

• CAT Number: R001179
• CAS Number: 18861-78-4
• Molecular Formula: C21H11NO5S
• Molecular Weight: 389.38
• Purity: ≥95%
• Synonyms: 3′,6′-dihydroxy-5-isothiocyanatospiro[2-benzofuran-3,9′-xanthene]-1-one
• InChI: InChI=1S/C21H11NO5S/c23-12-2-5-15-18(8-12)26-19-9-13(24)3-6-16(19)21(15)17-7-11(22-10-28)1-4-14(17)20(25)27-21/h1-9,23-24H
• InChIKey: GTQFZXYECNSNNC-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=C1N=C=S)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O

Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with Kds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively[1].

Reference

[1]. Swindlehurst CA, et al. Fluorescence measurements of immune complexes of Mab 4-4-20 with isomeric haptens. Biophys J. 1991 Mar;59(3):619-28.
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