For research use only. Not for therapeutic Use.
Fluorescein-CM2 is a fluorogenic molecule that can be used to rapidly screen esterase cut sites for protein-protein interaction-dependent (PPI-dependent) esterase activity in E. coli[1].
| Catalog Number | I040063 |
| CAS Number | 1394821-44-3 |
| Synonyms | [6′-[(1-methylcyclopropanecarbonyl)oxymethoxy]-3-oxospiro[2-benzofuran-1,9′-xanthene]-3′-yl]oxymethyl 1-methylcyclopropane-1-carboxylate |
| Molecular Formula | C32H28O9 |
| Purity | ≥95% |
| InChI | InChI=1S/C32H28O9/c1-30(11-12-30)28(34)38-17-36-19-7-9-23-25(15-19)40-26-16-20(37-18-39-29(35)31(2)13-14-31)8-10-24(26)32(23)22-6-4-3-5-21(22)27(33)41-32/h3-10,15-16H,11-14,17-18H2,1-2H3 |
| InChIKey | CEDGSMZXLBPDNN-UHFFFAOYSA-N |
| SMILES | CC1(CC1)C(=O)OCOC2=CC3=C(C=C2)C4(C5=C(O3)C=C(C=C5)OCOC(=O)C6(CC6)C)C7=CC=CC=C7C(=O)O4 |
| Reference | [1]. Jones KA, et al. Development of a Split Esterase for Protein-Protein Interaction-Dependent Small-Molecule Activation. ACS Cent Sci. 2019 Nov 27;5(11):1768-1776. |
