Fluoxetine

For research use only. Not for therapeutic Use.

  • CAT Number: I004030
  • CAS Number: 54910-89-3
  • Molecular Formula: C17H18F3NO
  • Molecular Weight: 309.33
  • Purity: ≥95%
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Fluoxetine (Cat.No:I004030) is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed as an antidepressant. It works by increasing the levels of serotonin in the brain, helping to alleviate symptoms of depression, anxiety, and other mood disorders. Fluoxetine is also used in the treatment of bulimia nervosa, obsessive-compulsive disorder, and panic disorder.


Catalog Number I004030
CAS Number 54910-89-3
Molecular Formula C17H18F3NO
Purity ≥95%
Target SSRIs
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
InChIKey RTHCYVBBDHJXIQ-UHFFFAOYSA-N
SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
Reference

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<br>[1]. Palvimaki, E.P., et al., Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berl), 1996. 126(3): p. 234-40.

<br>[2]. Fuller, R.W., K.W. Perry, and B.B. Molloy, Effect of an uptake inhibitor on serotonin metabolism in rat brain: studies with 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine (Lilly 110140). Life Sci, 1974. 15(6): p. 1161-71.

<br>[3]. Narita, N., et al., Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain. Eur J Pharmacol, 1996. 307(1): p. 117-9.

<br>[4]. Hashimoto, K., Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship. Cent Nerv Syst Agents Med Chem, 2009. 9(3): p. 197-204.

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