For research use only, not for therapeutic use.
Fluralaner is a systemic insecticide and acaricide belonging to the isoxazoline class, widely used in veterinary medicine to control fleas and ticks in dogs and cats. It works by inhibiting the nervous system of parasites, specifically blocking ligand-gated chloride channels (GABA and glutamate receptors), leading to hyperexcitation, paralysis, and death of the pests. Fluralaner is administered orally or topically and provides long-lasting protection, often effective for up to 12 weeks with a single dose. Its efficacy and prolonged action make it a popular choice for protecting pets from parasitic infestations.
Catalog Number | I006822 |
CAS Number | 864731-61-3 |
Synonyms | AH252723; AH-252723; AH 252723; A-1443; A1443; A 1443; Fluralaner, trade name: Bravecto.;4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide |
Molecular Formula | C22H17Cl2F6N3O3 |
Purity | ≥95% |
Solubility | Soluble in DMSO, not in water |
Storage | -20°C |
IUPAC Name | 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide |
InChI | InChI=1S/C22H17Cl2F6N3O3/c1-11-4-12(2-3-16(11)19(35)31-9-18(34)32-10-21(25,26)27)17-8-20(36-33-17,22(28,29)30)13-5-14(23)7-15(24)6-13/h2-7H,8-10H2,1H3,(H,31,35)(H,32,34) |
InChIKey | MLBZKOGAMRTSKP-UHFFFAOYSA-N |
SMILES | CC1=CC(C2=NOC(C3=CC(Cl)=CC(Cl)=C3)(C(F)(F)F)C2)=CC=C1C(NCC(NCC(F)(F)F)=O)=O |