Fluralaner

For research use only, not for therapeutic use.

  • CAT Number: I006822
  • CAS Number: 864731-61-3
  • Molecular Formula: C22H17Cl2F6N3O3
  • Molecular Weight: 556.3
  • Purity: ≥95%
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Fluralaner is a systemic insecticide and acaricide belonging to the isoxazoline class, widely used in veterinary medicine to control fleas and ticks in dogs and cats. It works by inhibiting the nervous system of parasites, specifically blocking ligand-gated chloride channels (GABA and glutamate receptors), leading to hyperexcitation, paralysis, and death of the pests. Fluralaner is administered orally or topically and provides long-lasting protection, often effective for up to 12 weeks with a single dose. Its efficacy and prolonged action make it a popular choice for protecting pets from parasitic infestations.


Catalog Number I006822
CAS Number 864731-61-3
Synonyms

AH252723; AH-252723; AH 252723; A-1443; A1443; A 1443; Fluralaner, trade name: Bravecto.;4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide

Molecular Formula C22H17Cl2F6N3O3
Purity ≥95%
Solubility Soluble in DMSO, not in water
Storage -20°C
IUPAC Name 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide
InChI InChI=1S/C22H17Cl2F6N3O3/c1-11-4-12(2-3-16(11)19(35)31-9-18(34)32-10-21(25,26)27)17-8-20(36-33-17,22(28,29)30)13-5-14(23)7-15(24)6-13/h2-7H,8-10H2,1H3,(H,31,35)(H,32,34)
InChIKey MLBZKOGAMRTSKP-UHFFFAOYSA-N
SMILES CC1=CC(C2=NOC(C3=CC(Cl)=CC(Cl)=C3)(C(F)(F)F)C2)=CC=C1C(NCC(NCC(F)(F)F)=O)=O

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