Flurbiprofen-d3

• CAT Number: R005805
• CAS Number: 1185133-81-6
• Molecular Formula: C15H13FO2
• Molecular Weight: 247.28
• Purity: ≥95%
• Synonyms: 2-Fluoro-α-(methyl-d3)-[1,1’-biphenyl]-4-acetic Acid; 3-Fluoro-4-phenylhydratropic Acid-d3; (+/-)-Flurbiprofen-d3; 2-Fluoro-α-(methyl-d3)-4-diphenylacetic Acid; Adfeed-d3; Ansaid-d3; Flurofen-d3; Froben-d3; Stayban-d3; U 27182-d3; Zepolas-d3; dl-2-(
• Storage: -20°C
• IUPAC Name: 3,3,3-trideuterio-2-(3-fluoro-4-phenylphenyl)propanoic acid
• InChI: InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/i1D3
• InChIKey: SYTBZMRGLBWNTM-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])C(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

Flurbiprofen-d3(Cat No.: R005805) is a deuterium-labeled derivative of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID). Its mode of action involves inhibiting the cyclooxygenase enzymes, COX-1 and COX-2, thereby reducing the production of prostaglandins that mediate pain, inflammation, and fever. The deuterium labeling in flurbiprofen-d3 serves as a tracer for pharmacokinetic studies or bioavailability assessments. Flurbiprofen-d3’s applications lie in pharmacokinetics and drug metabolism research, aiding in understanding how the parent compound is absorbed, distributed, metabolized, and excreted. Its incorporation into studies provides insights into the fate of flurbiprofen in the body and contributes to refining dosing regimens and optimizing drug therapies.