Flutazolam

• CAT Number: I011907
• CAS Number: 27060-91-9
• Molecular Formula: C19H18ClFN2O3
• Molecular Weight: 376.812
• Purity: ≥95%
• Synonyms: Flutazolam; Coreminal; MS-4101; MS 4101; MS4101; Ro 7-6102; Ro7-6102; Ro-7-6102.;10-Chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
• Solubility: Soluble in DMSO
• Storage: Store at 0-8 °C
• IUPAC Name: 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
• InChI: InChI=1S/C19H18ClFN2O3/c20-13-5-6-17-15(11-13)19(14-3-1-2-4-16(14)21)22(8-10-26-19)12-18(25)23(17)7-9-24/h1-6,11,24H,7-10,12H2
• InChIKey: WMFSSTNVXWNLKI-UHFFFAOYSA-N
• SMILES: C1COC2(N1CC(=O)N(C3=C2C=C(C=C3)Cl)CCO)C4=CC=CC=C4F

Flutazolam, also known as Coreminal; MS-4101 and Ro 7-6102, is a drug which is a benzodiazepine derivative. It was invented in Japan, and this is the main country in which it has been used medically. It has sedative, muscle relaxant, anticonvulsant, and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and though it/’s around the same potency as diazepam, it produces a more marked sedation and impaired coordination. It is indicated for the treatment of insomnia. Flutazolam is closely related in structure to another benzodiazepine, haloxazolam.