Fluticasone propionate-d5（Cat No.:S000856） is a deuterated variant of fluticasone propionate, where five hydrogen atoms are replaced with deuterium, resulting in the molecular formula C25H26D5F3O5S. This stable isotope-labeled compound is essential in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy for enhanced detection and precise quantification in the study of respiratory drug metabolism. Fluticasone propionate-d5 is widely used in pharmaceutical research to explore the pharmacokinetics and dynamics of this corticosteroid, crucial for treating asthma and allergic rhinitis, aiding in the development of effective dosing regimens and improved inhalation therapies.
| Catalog Number | S000856 |
| CAS Number | 1093258-28-6 |
| Molecular Formula | C25H26D5F3O5S |
| Purity | ≥95% |
| IUPAC Name | [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] 2,2,3,3,3-pentadeuteriopropanoate |
| InChI | InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1/i1D3,5D2 |
| InChIKey | WMWTYOKRWGGJOA-AMTWIDTLSA-N |
| SMILES | CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF |
