Fmoc-​N-​benzylglycine

• CAT Number: R035675
• CAS Number: 141743-13-7
• Molecular Formula: C24H21NO4
• Molecular Weight: 387.435
• Purity: ≥95%
• Synonyms: N-​α-​(9-​Fluorenylmethyloxyca​rbonyl)​-​N-​α-​benzyl Glycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(phenylmethyl)glycine; 2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl](benzyl)amino]acetic Acid; 216: PN: US20070042401 PAGE: 29 Claimed Protein; 907: PN: W
• Storage: Store at -20C
• IUPAC Name: 2-[benzyl(9H-fluoren-9-ylmethoxycarbonyl)amino]acetic acid
• InChI: InChI=1S/C24H21NO4/c26-23(27)15-25(14-17-8-2-1-3-9-17)24(28)29-16-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22H,14-16H2,(H,26,27)
• InChIKey: IZXYZVSMRGDEOQ-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CN(CC(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Fmoc-N-benzylglycine is a derivative of glycine, modified with an N-benzyl group and protected by an Fmoc (9-fluorenylmethyloxycarbonyl) group. It is primarily used in peptide synthesis, where the Fmoc group provides temporary protection of the amino group, allowing for controlled stepwise reactions. The benzyl group attached to the glycine backbone offers additional structural variety, making it valuable in the development of peptides with unique biological properties. Fmoc-N-benzylglycine is a critical intermediate in solid-phase peptide synthesis, contributing to the creation of complex peptides for pharmaceutical research, drug development, and bioactive compound studies.