Fmoc-3-amino-4,4,4-trifluorobutyric acid

• CAT Number: L020329
• CAS Number: 194471-86-8
• Molecular Formula: C19H16F3NO4
• Molecular Weight: 379.30
• Purity: ≥95%
• IUPAC Name: 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4,4,4-trifluorobutanoic acid
• InChI: InChI=1S/C19H16F3NO4/c20-19(21,22)16(9-17(24)25)23-18(26)27-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H,23,26)(H,24,25)
• InChIKey: WCJXAGGMJPEDDU-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C(F)(F)F

Fmoc-3-amino-4,4,4-trifluorobutyric acid（Cat No.:L020329）is a fluorinated amino acid derivative, protected with a 9-fluorenylmethoxycarbonyl (Fmoc) group, widely used in peptide synthesis and medicinal chemistry. The trifluoromethyl group enhances the compound’s lipophilicity and stability, making it valuable for designing peptides with improved pharmacokinetic properties. This compound serves as a building block in the synthesis of fluorinated peptides and proteins, offering unique reactivity and structural features. Researchers utilize it to develop novel therapeutic agents, studying its effects on biological activity and metabolic stability in drug design.