Fmoc-amino-PEG5-acid

• CAT Number: I015617
• CAS Number: 882847-32-7
• Molecular Formula: C₂₈H₃₇NO₉
• Molecular Weight: 531.59
• Purity: ≥95%
• Target: PROTAC Linkers
• Storage: 2-8°C
• IUPAC Name: 3-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C28H37NO9/c30-27(31)9-11-33-13-15-35-17-19-37-20-18-36-16-14-34-12-10-29-28(32)38-21-26-24-7-3-1-5-22(24)23-6-2-4-8-25(23)26/h1-8,26H,9-21H2,(H,29,32)(H,30,31)
• InChIKey: TWQTXZPTZPOEEB-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCC(=O)O

Fmoc-amino-PEG5-acid（Cat No.:I015617）, is a chemical compound used in the field of organic synthesis and peptide chemistry. It consists of an amino-PEG (polyethylene glycol) backbone with five ethylene glycol units, and it is protected with a Fmoc (fluorenylmethyloxycarbonyl) group. This compound is commonly utilized as a building block for the construction of peptide-PEG conjugates and other bioconjugates. It provides water solubility, flexibility, and selective deprotection properties, making it valuable for modifying peptides and proteins in various research and medical applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562