Fmoc-aminooxy-PEG2-NH2

For research use only. Not for therapeutic Use.

  • CAT Number: I045432
  • CAS Number: 190249-87-7
  • Molecular Formula: C19H22N2O5
  • Molecular Weight: 358.39
  • Purity: ≥95%
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Fmoc-aminooxy-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.


Catalog Number I045432
CAS Number 190249-87-7
Synonyms

9H-fluoren-9-ylmethyl N-[2-(2-aminooxyethoxy)ethoxy]carbamate

Molecular Formula C19H22N2O5
Purity ≥95%
InChI InChI=1S/C19H22N2O5/c20-25-11-9-23-10-12-26-21-19(22)24-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,18H,9-13,20H2,(H,21,22)
InChIKey PJENKAHPGFOITB-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NOCCOCCON
Reference

[1]. Siekmann J, et, al. Materials and methods for conjugating a water soluble fatty acid derivative to a protein. US20120190096A1.

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