Fmoc-Cys(Acm)-OH

• CAT Number: L046056
• CAS Number: 86060-81-3
• Molecular Formula: C21H22N2O5S
• Molecular Weight: 414.51
• Purity: ≥95%
• IUPAC Name: (2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• InChI: InChI=1S/C21H22N2O5S/c1-13(24)22-12-29-11-19(20(25)26)23-21(27)28-10-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,18-19H,10-12H2,1H3,(H,22,24)(H,23,27)(H,25,26)/t19-/m0/s1
• InChIKey: CSMYOORPUGPKAP-IBGZPJMESA-N

Fmoc-Cys(Acm)-OH(CAT: L046056) is a protected cysteine derivative widely used in peptide synthesis, particularly when sulfur-containing side chains are involved. In this compound, the amino group is protected with an Fmoc (9-fluorenylmethyloxycarbonyl) group, while the thiol group of cysteine is protected with an Acm (acetamidomethyl) group. This dual protection strategy allows for selective deprotection of either the amine or thiol groups during synthesis, offering precision in multi-step reactions. Fmoc-Cys(Acm)-OH is essential for the synthesis of complex peptides and proteins where maintaining thiol integrity is critical, making it highly valued in research focused on disulfide-bonded structures, redox studies, and protein folding analysis.