Fmoc-Gly-Gly-Phe-OtBu

• CAT Number: I017658
• CAS Number: 236426-37-2
• Molecular Formula: C₃₂H₃₅N₃O₆
• Molecular Weight: 557.64
• Purity: ≥95%
• Target: ADC Linker
• IUPAC Name: tert-butyl (2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoate
• InChI: InChI=1S/C32H35N3O6/c1-32(2,3)41-30(38)27(17-21-11-5-4-6-12-21)35-29(37)19-33-28(36)18-34-31(39)40-20-26-24-15-9-7-13-22(24)23-14-8-10-16-25(23)26/h4-16,26-27H,17-20H2,1-3H3,(H,33,36)(H,34,39)(H,35,37)/t27-/m0/s1
• InChIKey: XQLGBXCTOOARCT-MHZLTWQESA-N
• SMILES: CC(C)(C)OC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Fmoc-Gly-Gly-Phe-OtBu (Cat No.:I017658) is a commonly used linker for cleavable antibody-drug conjugates (ADCs). If you need, please contact us in time, and we will reply as soon as possible within 24 hours.

Reference

[1]. Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.