Fmoc-Gly-NH-CH2-O-CH2COOH

• CAT Number: I040762
• CAS Number: 1599440-08-0
• Molecular Formula: C20H20N2O6
• Molecular Weight: 384.38
• Purity: ≥95%
• Synonyms: 2-[[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]methoxy]acetic acid
• InChI: InChI=1S/C20H20N2O6/c23-18(22-12-27-11-19(24)25)9-21-20(26)28-10-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,21,26)(H,22,23)(H,24,25)
• InChIKey: LIBCNUNKCWYZAX-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCOCC(=O)O

Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs[1].

Reference

[1]. Tsuda Toshifumi, et al. Novel cyclic dinucleotide derivative and its antibody-drug conjugate having STING agonist activity. Patent. WO2020050406.