Fmoc-Gly-NH-CH2-O-CH2COOH

• CAT Number: I040762
• CAS Number: 1599440-08-0
• Molecular Formula: C20H20N2O6
• Molecular Weight: 384.38
• Purity: ≥95%
• Synonyms: 2-[[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]methoxy]acetic acid
• InChI: InChI=1S/C20H20N2O6/c23-18(22-12-27-11-19(24)25)9-21-20(26)28-10-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,21,26)(H,22,23)(H,24,25)
• InChIKey: LIBCNUNKCWYZAX-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCOCC(=O)O

Fmoc-Gly-NH-CH₂-O-CH₂COOH(CAT: I040762) is a protected glycine derivative commonly used in solid-phase peptide synthesis (SPPS). It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the amino terminus and a unique linker structure involving an ether and carboxylic acid moiety. This compound is useful as a building block or linker in the synthesis of modified peptides or peptidomimetics, particularly where additional spacing or functionalization is required between the glycine residue and the growing peptide chain. Its design allows for flexible incorporation into peptide backbones while maintaining compatibility with standard Fmoc-based synthesis protocols.