Fmoc-L-γ-azidohomoalanine

• CAT Number: R068667
• CAS Number: 942518-20-9
• Molecular Formula: C19H18N4O4
• Molecular Weight: 366.377
• Purity: ≥95%
• Synonyms: (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-azidobutanoic acid;Fmoc-Azh-OH
• Storage: Store at 0-8 °C
• IUPAC Name: (2S)-4-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid
• InChI: InChI=1S/C19H18N4O4/c20-23-21-10-9-17(18(24)25)22-19(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,22,26)(H,24,25)/t17-/m0/s1
• InChIKey: CLEZARXVEABQBI-KRWDZBQOSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCN=[N+]=[N-])C(=O)O

Fmoc-L-γ-azidohomoalanine is an Fmoc-protected amino acid derivative featuring an azido group on the γ-position of homoalanine. It is widely used in peptide synthesis and bioorthogonal chemistry, with the azide group enabling selective click chemistry reactions, such as the Staudinger ligation or Cu-catalyzed azide-alkyne cycloaddition. This compound is valuable for creating modified peptides and proteins for research purposes, particularly in studying protein interactions, labeling, and functional analysis, making it essential for chemical biology and drug development.