Fmoc-L-b-methylisoleucine

• CAT Number: I043243
• CAS Number: 1227750-73-3
• Molecular Formula: C22H25NO4
• Molecular Weight: 367.44
• Purity: ≥95%
• Synonyms: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3,3-dimethylpentanoic acid
• InChI: InChI=1S/C22H25NO4/c1-4-22(2,3)19(20(24)25)23-21(26)27-13-18-16-11-7-5-9-14(16)15-10-6-8-12-17(15)18/h5-12,18-19H,4,13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m1/s1
• InChIKey: KTFMEQGAIAYJMN-LJQANCHMSA-N
• SMILES: CCC(C)(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Fmoc-L-b-methylisoleucine is an amino acid derivative that can be used for compound synthesis[1].

Reference

[1]. Nicolaou KC, et al. Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates. J Am Chem Soc. 2018 Mar 14;140(10):3690-3711.
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