Fmoc-L-Lys(pentynoyl)-OH

• CAT Number: L003141
• CAS Number: 1159531-18-6
• Molecular Formula: C26H28N2O5
• Molecular Weight: 448.5
• Purity: ≥95%
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-(pent-4-ynoylamino)hexanoic acid
• InChI: InChI=1S/C26H28N2O5/c1-2-3-15-24(29)27-16-9-8-14-23(25(30)31)28-26(32)33-17-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1,4-7,10-13,22-23H,3,8-9,14-17H2,(H,27,29)(H,28,32)(H,30,31)/t23-/m0/s1
• InChIKey: ZEXYNDUFTOOVKN-QHCPKHFHSA-N
• SMILES: C#CCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Fmoc-L-Lys(pentynoyl)-OH is a derivative of lysine, featuring a fluorenylmethyloxycarbonyl (Fmoc) protective group and a pentynoyl substituent at the ε-amino group. This compound is valuable in peptide synthesis, as the Fmoc group protects the amine during coupling reactions while allowing for deprotection under mild conditions. The pentynoyl group provides additional functionality for further modifications or conjugations. This compound serves as an important building block in the synthesis of biologically active peptides and in exploring structure-activity relationships in drug development.