For research use only. Not for therapeutic Use.
Fmoc-Lys (biotin-PEG4)-OH(Cat No.:I014386)is a synthetic amino acid derivative used in peptide synthesis and bio-conjugation applications. It consists of a lysine (Lys) residue attached to a biotin moiety through a polyethylene glycol (PEG4) linker, with an Fmoc (9-fluorenylmethyloxycarbonyl) protective group. The Fmoc group is used to protect the amino group during peptide synthesis and can be removed under basic conditions. The biotin tag allows for easy detection or purification via avidin/streptavidin binding, while the PEG4 spacer enhances solubility and reduces steric hindrance, making it useful in various biochemical and molecular biology experiments.
Catalog Number | I014386 |
CAS Number | 1334172-64-3 |
Synonyms | Fmoc-Lys (biotin-PEG4)-OH;27-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5,21-dioxo-1-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-9,12,15,18-tetraoxa-6,22-diazaoctacosan-28-oic acid |
Molecular Formula | C42H59N5O11S |
Purity | ≥95% |
Target | PROTAC Linkers |
Solubility | Soluble in DMSO |
IUPAC Name | (2S)-6-[3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid |
InChI | InChI=1S/C42H59N5O11S/c48-37(15-6-5-14-36-39-35(28-59-36)45-41(52)47-39)44-18-20-55-22-24-57-26-25-56-23-21-54-19-16-38(49)43-17-8-7-13-34(40(50)51)46-42(53)58-27-33-31-11-3-1-9-29(31)30-10-2-4-12-32(30)33/h1-4,9-12,33-36,39H,5-8,13-28H2,(H,43,49)(H,44,48)(H,46,53)(H,50,51)(H2,45,47,52)/t34-,35-,36-,39-/m0/s1 |
InChIKey | PNYHBAKBBQCIDX-FWIWLVIWSA-N |
SMILES | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)NC(=O)N2 |