Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH

• CAT Number: I007709
• CAS Number: 911838-56-7
• Molecular Formula: C₃₃H₄₃N₃O₈
• Molecular Weight: 609.71
• Purity: ≥95%
• IUPAC Name: (4S,5R)-3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoyl]-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid
• InChI: InChI=1S/C33H43N3O8/c1-20-27(29(38)39)36(33(5,6)43-20)28(37)26(17-11-12-18-34-30(40)44-32(2,3)4)35-31(41)42-19-25-23-15-9-7-13-21(23)22-14-8-10-16-24(22)25/h7-10,13-16,20,25-27H,11-12,17-19H2,1-6H3,(H,34,40)(H,35,41)(H,38,39)/t20-,26+,27+/m1/s1
• InChIKey: JAHDJVRHKPYPNY-PHXCCWLDSA-N
• SMILES: C[C@@H]1[C@H](N(C(O1)(C)C)C(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O

Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH (Cat.No:I007709) is a modified amino acid derivative used in peptide synthesis. It contains Fmoc (fluorenylmethyloxycarbonyl) and Boc (tert-butyloxycarbonyl) protecting groups, enabling selective deprotection and coupling during peptide assembly. The inclusion of Thr(psi(Me,Me)pro) enhances the stability and conformational properties of the peptide. It finds applications in peptide research and drug development.

Reference

[1]. Michal Pechar, et al. Coiled coil peptides and polymer-peptide conjugates: synthesis, self-assembly, characterization and potential in drug delivery systems. Biomacromolecules. 2014 Jul 14;15(7):2590-9.