For research use only. Not for therapeutic Use.
Fmoc-NH-PEG10-acid (CAT: I015981) is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTACs (Proteolysis-Targeting Chimeras). PROTACs are innovative molecules designed to degrade specific target proteins within cells, offering a novel approach to drug discovery. This linker consists of a polyethylene glycol (PEG) chain with ten ethylene glycol units and a Fmoc-protected amino group. It facilitates the conjugation of a ligand for a target protein on one end and a ligand for an E3 ubiquitin ligase on the other end.
| Catalog Number | I015981 |
| CAS Number | 2101563-45-3 |
| Molecular Formula | C₃₈H₅₇NO₁₄ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
