Fmoc-NH-PEG4-CH2CH2COOH

• CAT Number: I016733
• CAS Number: 557756-85-1
• Molecular Formula: C₂₆H₃₃NO₈
• Molecular Weight: 487.54
• Purity: ≥95%
• Target: PROTAC
• Storage: -20°C
• IUPAC Name: 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
• InChIKey: NUHRPLKTAAVHCZ-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCC(=O)O

Fmoc-NH-PEG4-CH2CH2COOH (Cat No.:I016733) is a degradable ADC linker for antibody-drug conjugate (ADC) synthesis. Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.