Fmoc-NH-PEG9-CH2CH2COOH

• CAT Number: I017039
• CAS Number: 1191064-81-9
• Molecular Formula: C₃₆H₅₃NO₁₃
• Molecular Weight: 707.8
• Purity: ≥95%
• Target: PROTAC
• Storage: 2-8°C
• IUPAC Name: 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C36H53NO13/c38-35(39)9-11-41-13-15-43-17-19-45-21-23-47-25-27-49-28-26-48-24-22-46-20-18-44-16-14-42-12-10-37-36(40)50-29-34-32-7-3-1-5-30(32)31-6-2-4-8-33(31)34/h1-8,34H,9-29H2,(H,37,40)(H,38,39)
• InChIKey: NEESTRVILHNOJT-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

Fmoc-NH-PEG9-CH2CH2COOH (Cat No.:I017039) is a degradable ADC linker for antibody-drug conjugate (ADC) synthesis. Fmoc-NH-PEG9-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Yang Y,et al. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 Nov 1;24(21):5393-5399.