Fmoc-PEA

• CAT Number: I018035
• CAS Number: 329223-23-6
• Molecular Formula: C₁₇H₁₈NO₆P
• Molecular Weight: 363.3
• Purity: ≥95%
• Target: ADC Linker
• IUPAC Name: 9H-fluoren-9-ylmethyl N-(2-phosphonooxyethyl)carbamate
• InChI: InChI=1S/C17H18NO6P/c19-17(18-9-10-24-25(20,21)22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,18,19)(H2,20,21,22)
• InChIKey: YHUHBHVNOVAEMP-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOP(=O)(O)O

Fmoc-PEA (Cat.No:I018035) is a chemical compound used in peptide synthesis and solid-phase peptide synthesis (SPPS). It is derived from the amino acid phenylalanine and contains a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group. Fmoc-PEA serves as a building block for the synthesis of various peptides and peptide derivatives with diverse biological and pharmaceutical applications.

Reference

[1]. GARBACCIO, Robert, M., et al. PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES. WO2015153401A1.