Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB

• CAT Number: I016630
• CAS Number: 2055042-69-6
• Molecular Formula: C₆₀H₆₆N₆O₁₁
• Molecular Weight: 1047.2
• Purity: ≥95%
• Target: ADC Linker

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Reference

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.