Fmoc-(R)-2-tetrahydroisoquinoline acetic acid

• CAT Number: L023149
• CAS Number: 332064-67-2
• Molecular Formula: C26H23NO4
• Molecular Weight: 413.5
• Purity: ≥95%
• IUPAC Name: 2-[(3R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-3,4-dihydro-1H-isoquinolin-3-yl]acetic acid
• InChI: InChI=1S/C26H23NO4/c28-25(29)14-19-13-17-7-1-2-8-18(17)15-27(19)26(30)31-16-24-22-11-5-3-9-20(22)21-10-4-6-12-23(21)24/h1-12,19,24H,13-16H2,(H,28,29)/t19-/m1/s1
• InChIKey: ZYNHEOMLCMDTDW-LJQANCHMSA-N
• SMILES: C1[C@@H](N(CC2=CC=CC=C21)C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O

Fmoc-(R)-2-tetrahydroisoquinoline acetic acid is a derivative of tetrahydroisoquinoline, characterized by an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the amine, and an acetic acid moiety. This structure enhances its utility in peptide synthesis and drug development, allowing for selective reactions while protecting the amine functionality. The tetrahydroisoquinoline core is of interest in medicinal chemistry due to its potential biological activities, including neuroprotective effects. This compound can serve as a key intermediate in the synthesis of bioactive pharmaceuticals and complex molecules.