Fmoc-Val-Ala-aminomethyl acetate

• CAT Number: I040539
• CAS Number: 2505045-86-1
• Molecular Formula: C26H31N3O6
• Molecular Weight: 481.54
• Purity: ≥95%
• Synonyms: [[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]propanoyl]amino]methyl acetate
• InChI: InChI=1S/C26H31N3O6/c1-15(2)23(25(32)28-16(3)24(31)27-14-35-17(4)30)29-26(33)34-13-22-20-11-7-5-9-18(20)19-10-6-8-12-21(19)22/h5-12,15-16,22-23H,13-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t16-,23-/m0/s1
• InChIKey: MZBRJYLMNFPXHD-HJPURHCSSA-N
• SMILES: CC(C)C(C(=O)NC(C)C(=O)NCOC(=O)C)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs[1].

Reference

[1]. Charng-Sheng TSAI, et al. Antibody drug conjugates. Patent. WO2023125530