Fmoc-Val-Cit-PAB

• CAT Number: I002029
• CAS Number: 159858-22-7
• Molecular Formula: C33H39N5O6
• Molecular Weight: 601.69
• Purity: ≥95%
• Target: ADC Linker
• Solubility: DMSO: ≥ 123.75 mg/mL
• Storage: -20°C
• IUPAC Name: 9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
• InChI: InChI=1S/C33H39N5O6/c1-20(2)29(38-33(43)44-19-27-25-10-5-3-8-23(25)24-9-4-6-11-26(24)27)31(41)37-28(12-7-17-35-32(34)42)30(40)36-22-15-13-21(18-39)14-16-22/h3-6,8-11,13-16,20,27-29,39H,7,12,17-19H2,1-2H3,(H,36,40)(H,37,41)(H,38,43)(H3,34,35,42)/t28-,29-/m0/s1
• InChIKey: DALMAZHDNFCDRP-VMPREFPWSA-N
• SMILES: CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Fmoc-Val-Cit-PAB (Cat No.: I002029) is a cleavable antibody-drug conjugate (ADC) linker widely employed in laboratory research and chemical pharmaceutical synthesis. This versatile linker plays a crucial role in the development of ADCs, allowing for the precise and controlled delivery of potent cytotoxic drugs to target cells. It is a key component in the synthesis process, enabling the creation of ADCs for therapeutic applications, particularly in cancer treatment. Researchers rely on Fmoc-Val-Cit-PAB to advance their studies in the field of targeted drug delivery, making it an essential tool in pharmaceutical research and development.