For research use only. Not for therapeutic Use.
Fonazine, also known as Dimetotiazine, is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.
| Catalog Number | I006829 |
| CAS Number | 7456-24-8 |
| Synonyms | Fonazine; Dimetotiazine; Dimethothiazine; Dimetiotazine; Banistyl; Dimethodin; fonazine mesylate; fonazine monomesylate ;Migristene; Promaquid.;10-(2-(Dimethylamino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide |
| Molecular Formula | C19H25N3O2S2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4°C for short term or -20 °C for long term |
| IUPAC Name | 10-[2-(dimethylamino)propyl]-N,N-dimethylphenothiazine-2-sulfonamide |
| InChI | InChI=1S/C19H25N3O2S2/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5/h6-12,14H,13H2,1-5H3 |
| InChIKey | VWNWVCJGUMZDIU-UHFFFAOYSA-N |
| SMILES | CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C |
| Reference | </br>1:Takagi H, Takashima M, Liou SY. [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. Nihon Yakurigaku Zasshi. 1998 May;111(5):309-16. Japanese. PubMed PMID: 9666486. |
