Formononetin

• CAT Number: I003709
• CAS Number: 485-72-3
• Molecular Formula: C16H12O4
• Molecular Weight: 268.3
• Purity: ≥95%
• Synonyms: Biochanin B;NSC 93360
• Target: anti-cancer
• Solubility: DMSO: 200 mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: 7-hydroxy-3-(4-methoxyphenyl)chromen-4-one
• InChI: InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
• InChIKey: HKQYGTCOTHHOMP-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O

Formononetin (Cat.No:I003709) is a natural isoflavone found in various plants, including red clover and soybeans. It exhibits antioxidant, anti-inflammatory, and estrogenic properties. Formononetin has been studied for its potential health benefits, including its role in promoting bone health, cardiovascular protection, and anticancer effects. 

Reference

[1]. Liu XJ, et al. Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro. Asian Pac J Cancer Prev. 2014;15(6):2835-9.

[2]. Zhang X, et al. Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway. Nutr Cancer. 2014;66(4):656-61.

[3]. Chen J, et al. Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo. Horm Metab Res. 2011 Sep;43(10):681-6.