For research use only. Not for therapeutic Use.
Formycin A（Cat No.:I017268）is a nucleoside analog with broad-spectrum activity, widely studied in biochemical and pharmaceutical research. Structurally resembling adenosine, it interferes with nucleic acid metabolism, making it a potent inhibitor of purine biosynthesis and RNA-dependent processes. Formycin A exhibits antimicrobial, antiviral, and anticancer potential by disrupting critical enzymatic activities and replication pathways. It serves as a valuable tool for exploring nucleotide synthesis, enzyme mechanisms, and cellular metabolism. Researchers utilize Formycin A to study purine-related pathways and develop therapeutic strategies for infectious diseases and malignancies.
| Catalog Number | I017268 |
| CAS Number | 6742-12-7 |
| Molecular Formula | C₁₀H₁₃N₅O₄ |
| Purity | ≥95% |
| Target | Cell Cycle/DNA Damage |
| Storage | −20°C |
| IUPAC Name | (2S,3R,4S,5R)-2-(7-amino-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| InChI | InChI=1S/C10H13N5O4/c11-10-6-4(12-2-13-10)5(14-15-6)9-8(18)7(17)3(1-16)19-9/h2-3,7-9,16-18H,1H2,(H,14,15)(H2,11,12,13)/t3-,7-,8-,9+/m1/s1 |
| InChIKey | KBHMEHLJSZMEMI-KSYZLYKTSA-N |
| SMILES | C1=NC2=C(NN=C2C(=N1)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O |
| Reference | [1]. Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63.<br>[2]. Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). |
