For research use only. Not for therapeutic Use.
Foscarnet Sodium(Cat No.:A000570)is an antiviral agent primarily used to treat herpes viruses, including cytomegalovirus (CMV) and acyclovir-resistant herpes simplex virus (HSV) infections. Unlike other antivirals, it does not require activation by viral enzymes; instead, it directly inhibits viral DNA polymerase and reverse transcriptase, preventing viral replication. Foscarnet Sodium is administered intravenously, especially in immunocompromised patients such as those with HIV/AIDS, to manage severe or resistant infections. Its unique mechanism and broad antiviral spectrum make Foscarnet Sodium essential in managing complicated viral infections in clinical settings.
Catalog Number | A000570 |
CAS Number | 63585-09-1 |
Synonyms | 63585-09-1; Foscavir; Trisodium carboxyphosphate; Triapten; Foscarnet sodique |
Molecular Formula | CNa3O5P |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | trisodium;phosphonatoformate |
InChI | InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3 |
InChIKey | DFHAXXVZCFXGOQ-UHFFFAOYSA-K |
SMILES | C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+] |
Reference | 1: Yuan-Qu Y, Xiong-Pu M, Xiao-Kang J, Cai-An X. A comparison study on the <br> 3: Yu YY, Zhang DZ, Miao XH, Zhu CL, Zhou XQ, Yu H, Si CW. [Foscarnet sodium for 4: Gross G, Braun D. [Efficacy and tolerability of topical foscarnet sodium in 5: FDA notifications. FDA approves generic foscarnet sodium injection. AIDS 6: Stolk LM, Hendrikse H, Chandi LS. Autoclave and long-term sterility of 7: Iyer RP, Boal JH, Phillips LR, Thakker DR, Egan W. Synthesis, hydrolytic 8: Mathew M, Das Gupta V, Bethea C. Stability of foscarnet sodium in 5% dextrose 9: Woods K, Steinmann W, Bruns L, Neels JT. Stability of foscarnet sodium in 0.9% 10: DiStefano JE, Outman WR. Additional data on visual compatibility of foscarnet |