For research use only. Not for therapeutic Use.
Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect[1][2].
| Catalog Number | I041945 |
| CAS Number | 1802655-72-6 |
| Synonyms | [(3S,4R)-6-cyano-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromen-3-yl] dihydrogen phosphate |
| Molecular Formula | C16H19N2O6P |
| Purity | ≥95% |
| InChI | InChI=1S/C16H19N2O6P/c1-16(2)15(24-25(20,21)22)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)23-16/h5-6,8,14-15H,3-4,7H2,1-2H3,(H2,20,21,22)/t14-,15+/m1/s1 |
| InChIKey | JRUHOGHWZXTUMZ-CABCVRRESA-N |
| SMILES | CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)OP(=O)(O)O)C |
| Reference | [1]. Pervan-Steel CL, et al. Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (KATP) Channel Opening Prodrug. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):26. [2]. WHO Drug Information-World Health Organization (WHO). |
