For research use only. Not for therapeutic Use.
FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 µM. FOXM1-IN-1 shows antiproliferative activity. FOXM1-IN-1 decreases the the expression of FOXM1, PLK1, CDC25B protein[1].
FOXM1-IN-1 (0-10 μg/mL; 24 h) decreases the the expression of FOXM1, PLK1, CDC25B protein in SKOV3 cells[1].
| Catalog Number | I042378 |
| CAS Number | 2864407-22-5 |
| Synonyms | N-[2-[2-[4-[(4-chlorophenyl)methoxy]phenoxy]ethoxy]ethyl]cyclohexanamine |
| Molecular Formula | C23H30ClNO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H30ClNO3/c24-20-8-6-19(7-9-20)18-28-23-12-10-22(11-13-23)27-17-16-26-15-14-25-21-4-2-1-3-5-21/h6-13,21,25H,1-5,14-18H2 |
| InChIKey | RKTLOUYERGLRCM-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NCCOCCOC2=CC=C(C=C2)OCC3=CC=C(C=C3)Cl |
| Reference | [1]. Gao Y, et al. Synthesis and antineoplastic activity of ethylene glycol phenyl aminoethyl ether derivatives as FOXM1 inhibitors. Eur J Med Chem. 2022 Dec 15;244:114877. |
