FOXO1-IN-3

• CAT Number: I040925
• CAS Number: 2451093-95-9
• Molecular Formula: C22H23N7O
• Molecular Weight: 401.46
• Purity: ≥95%
• Synonyms: N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
• InChI: InChI=1S/C22H23N7O/c1-28-10-12-29(13-11-28)16-8-6-15(7-9-16)22(30)25-20-14-19(26-27-20)21-23-17-4-2-3-5-18(17)24-21/h2-9,14H,10-13H2,1H3,(H,23,24)(H2,25,26,27,30)
• InChIKey: OYUAMDGBOAEJOY-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)C4=NC5=CC=CC=C5N4

FOXO1-IN-3(CAT: I040925) is a selective inhibitor targeting FOXO1 (Forkhead box O1), a transcription factor involved in regulating various cellular processes such as apoptosis, metabolism, and oxidative stress response. FOXO1 plays a critical role in controlling cell survival, and its dysregulation is associated with diseases like cancer, diabetes, and cardiovascular conditions. By inhibiting FOXO1, FOXO1-IN-3 can modulate these pathways, potentially preventing tumor cell growth and improving metabolic dysfunctions. This compound is particularly relevant for Cancer Disease Research and Metabolic Disease Research, offering a promising therapeutic approach for diseases driven by FOXO1 dysregulation.