FPA 124

• CAT Number: I010652
• CAS Number: 902779-59-3
• Molecular Formula: C11H9Cl2CuN3O2S
• Molecular Weight: 381.70
• Purity: ≥95%
• Synonyms: Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex
• Target: Akt
• Solubility: Soluble to 10 mM in DMSO and to 10 mM in ethanol
• Storage: Store at 4℃
• IUPAC Name: dichlorocopper;[(Z)-(4-oxochromen-3-yl)methylideneamino]thiourea
• InChI: InChI=1S/C11H9N3O2S.2ClH.Cu/c12-11(17)14-13-5-7-6-16-9-4-2-1-3-8(9)10(7)15;;;/h1-6H,(H3,12,14,17);2*1H;/q;;;+2/p-2/b13-5-
• InChIKey: HZRXQEVFXXQYFS-KHDHKOIVSA-L
• SMILES: C1=CC=C2C(=C1)C(=O)C(=CO2)/C=N\NC(=S)N.Cl[Cu]Cl

FPA 124（Cat No.:I010652）is a potent and selective inhibitor of glycogen synthase kinase-3 beta (GSK-3β), an enzyme involved in various cellular processes such as inflammation, cell proliferation, and neurodegeneration. By inhibiting GSK-3β, FPA 124 has demonstrated neuroprotective effects, making it a valuable compound in research for neurodegenerative diseases like Alzheimer’s and Parkinson’s. It also exhibits anti-inflammatory properties, which may contribute to its potential therapeutic applications. FPA 124 is widely used in studies exploring the role of GSK-3β in disease pathogenesis and the development of novel therapeutic strategies.