For research use only. Not for therapeutic Use.
PL-13210(CAT: I027738) is a selective phospholipase A2 (PLA2) inhibitor, effectively blocking the enzymatic activity responsible for the release of arachidonic acid and subsequent eicosanoid production. This inhibition is crucial in the inflammation and immunology field, as it modulates inflammatory responses by reducing pro-inflammatory mediator synthesis. FPL-13210 is widely utilized in research to explore the role of PLA2 in inflammatory pathways, immune signaling, and related disorders. Its high specificity and efficacy provide reliable insights into therapeutic strategies targeting inflammation-related diseases, making it an essential tool for advancing pharmaceutical and biomedical research.
Catalog Number | I027738 |
CAS Number | 143305-97-9 |
Synonyms | FPL-13210; FPL 13210; FPL13210 |
Molecular Formula | C22H29BrN2O2 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | (S)-2-((R)-(2-bromophenyl)(hydroxy)methyl)-5-(dimethylamino)-N,N-dimethyl-2-phenylpentanamide |
InChI | InChI=1S/C22H29BrN2O2/c1-24(2)16-10-15-22(21(27)25(3)4,17-11-6-5-7-12-17)20(26)18-13-8-9-14-19(18)23/h5-9,11-14,20,26H,10,15-16H2,1-4H3/t20-,22-/m0/s1 |
InChIKey | JVKFYSJJNSJAEZ-UNMCSNQZSA-N |
SMILES | CN(C)CCC[C@](C1=CC=CC=C1)([C@H](C2=CC=CC=C2Br)O)C(=O)N(C)C |