FR106969

• CAT Number: I027758
• CAS Number: 50655-20-4
• Molecular Formula: C16H22N2O3S2
• Molecular Weight: 354.48
• Purity: 98%
• Synonyms: FR106969; FR 106969; FR-106969
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2,5-Piperazinedione, 3,6-bis(methylthio)-1,4-dimethyl-3-(hydroxymethyl)-6-(phenylmethyl)-
• InChI: InChI=1S/C16H22N2O3S2/c1-17-14(21)16(11-19,23-4)18(2)13(20)15(17,22-3)10-12-8-6-5-7-9-12/h5-9,19H,10-11H2,1-4H3
• InChIKey: WXIJHVRXTHDGKV-UHFFFAOYSA-N
• SMILES: O=C(C(CO)(SC)N1C)N(C)C(CC2=CC=CC=C2)(SC)C1=O

FR106969(CAT: I027758) is a naturally derived platelet-activating factor (PAF) antagonist, isolated from a fungal source. By blocking PAF receptors, it inhibits PAF-mediated signaling pathways, which are key drivers of inflammation, platelet aggregation, and vascular permeability. FR106969 exhibits potent anti-inflammatory properties, making it a valuable tool in immunology and pharmacology research. It is particularly useful for studying the role of PAF in inflammatory diseases, allergic responses, and thrombosis. Its natural origin and specificity provide insights into novel therapeutic approaches targeting PAF-related pathways in conditions such as asthma, sepsis, and autoimmune disorders.