FR191413

• CAT Number: I006876
• CAS Number: 194928-55-7
• Molecular Formula: C34H31Cl2N7O5
• Molecular Weight: 688.57
• Purity: ≥95%
• Synonyms: FR191413; FR 191413; FR-191413.;(E)-3-(6-acetamidopyridin-3-yl)-N-[2-[[2,4-dichloro-3-[[2-methoxy-1-(pyridin-2-ylmethyl)benzimidazol-4-yl]oxymethyl]phenyl]-methylamino]-2-oxoethyl]prop-2-enamide
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term or -20 °C for long term
• IUPAC Name: (E)-3-(6-acetamidopyridin-3-yl)-N-[2-[2,4-dichloro-3-[[2-methoxy-1-(pyridin-2-ylmethyl)benzimidazol-4-yl]oxymethyl]-N-methylanilino]-2-oxoethyl]prop-2-enamide
• InChI: InChI=1S/C34H31Cl2N7O5/c1-21(44)40-29-14-10-22(17-38-29)11-15-30(45)39-18-31(46)42(2)26-13-12-25(35)24(32(26)36)20-48-28-9-6-8-27-33(28)41-34(47-3)43(27)19-23-7-4-5-16-37-23/h4-17H,18-20H2,1-3H3,(H,39,45)(H,38,40,44)/b15-11+
• InChIKey: KXMCFJQQOFOBKN-RVDMUPIBSA-N
• SMILES: CC(=O)NC1=NC=C(C=C1)/C=C/C(=O)NCC(=O)N(C)C2=C(C(=C(C=C2)Cl)COC3=CC=CC4=C3N=C(N4CC5=CC=CC=N5)OC)Cl

FR191413（Cat No.:I006876）is a selective, potent antagonist of the tachykinin NK1 receptor, which is involved in mediating the effects of substance P, a neuropeptide linked to pain, inflammation, and other physiological processes. By blocking the NK1 receptor, FR191413 has potential therapeutic applications in treating conditions like chronic pain, nausea, anxiety, and depression. It has been investigated for its ability to reduce pain perception and alleviate symptoms of various disorders involving tachykinin signaling. Further research is needed to assess its safety, efficacy, and potential clinical applications in treating neurological and inflammatory conditions.